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Serotonin 5-HT₁ receptors potentiate histamine and thrombin stimulated prostaglandin synthesis in endothelial cellsKILBOURNE, Edward J; WINNEKER, Richard C.Thrombosis and haemostasis. 2001, Vol 85, Num 5, pp 924-928, issn 0340-6245Article

Aberrant expression of Cyr61, a member of the CCN (CTGF/Cyr61/Cef10/NOVH) family, and dysregulation by 17β-estradiol and basic fibroblast growth factor in human uterine leiomyomasSAMPATH, Deepak; YUAN ZHU; WINNEKER, Richard C et al.The Journal of clinical endocrinology and metabolism. 2001, Vol 86, Num 4, pp 1707-1715, issn 0021-972XArticle

Rat uterine complement C3 expression as a model for progesterone receptor modulators : characterization of the new progestin trimegestoneLUNDEEN, Scott G; ZHIMING ZHANG; YUAN ZHU et al.Journal of steroid biochemistry and molecular biology. 2001, Vol 78, Num 2, pp 137-143, issn 0960-0760Article

Down-regulation of endometrial matrix metalloproteinase-3 and -7 expression in vitro and therapeutic regression of experimental endometriosis in vivo by a novel nonsteroidal progesterone receptor agonist, tanaprogetBRUNER-TRAN, Kaylon L; ZHIMING ZHANG; EISENBERG, Esther et al.The Journal of clinical endocrinology and metabolism. 2006, Vol 91, Num 4, pp 1554-1560, issn 0021-972X, 7 p.Article

Dual acting norepinephrine reuptake inhibitors and 5-HT_2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indolesHEFFERNAN, GavinD; COGHLAN, Richard D; COSMI, Scott A et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 22, pp 7802-7815, issn 0968-0896, 14 p.Article

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)FENSOME, Andrew; ADAMS, William R; MELENSKI, Edward G et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 6, pp 1861-1873, issn 0022-2623, 13 p.Article

Discovery of a novel mechanism of steroid receptor antagonism: WAY-255348 modulates progesterone receptor cellular localization and promoter interactionsYUDT, Matthew R; RUSSO, Louise A; WROBEL, Jay et al.Biochemical pharmacology. 2011, Vol 82, Num 11, pp 1709-1719, issn 0006-2952, 11 p.Article

Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone-regulated gene markersCRABTREE, Judy S; XIAOCHUN ZHANG; PEANO, Bryan J et al.Journal of steroid biochemistry and molecular biology. 2006, Vol 101, Num 1, pp 11-21, issn 0960-0760, 11 p.Article

7-Aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs as non-steroidal progesterone receptor antagonistsPUWEN ZHANG; KERN, Jeffrey C; WROBEL, Jay et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 13, pp 6589-6600, issn 0968-0896, 12 p.Article

Development of an early biomarker for the ovarian liability of selective estrogen receptor modulators in ratsHARRIS, Heather A; CHENNATHUKUZHI, Vargheese M; WINNEKER, Richard C et al.Journal of steroid biochemistry and molecular biology. 2008, Vol 112, Num 1-3, pp 40-46, issn 0960-0760, 7 p.Article

Synthesis and structure-activity relationship of novel 6-aryl-1,4-dihydrobenzo[d][1,3]oxazine-2-thiones as progesterone receptor modulators leading to the potent and selective nonsteroidal progesterone receptor agonist tanaprogetFENSOME, Andrew; BENDER, Reinhold; TEREFENKO, Eugene A et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 16, pp 5092-5095, issn 0022-2623, 4 p.Article

Identification of novel estrogen receptor α antagonistsDALEI SHAO; BERRODIN, Thomas J; MANAS, Eric et al.Journal of steroid biochemistry and molecular biology. 2004, Vol 88, Num 4-5, pp 351-360, issn 0960-0760, 10 p.Article

Regulation of gene expression by PRA-910, a novel progesterone receptor modulator, in T47D cellsBRAY, Jeffrey D; ZHIMING ZHANG; WINNEKER, Richard C et al.Steroids. 2003, Vol 68, Num 10-13, pp 995-1003, issn 0039-128X, 9 p.Conference Paper

1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalene derivatives as non-steroidal progesterone receptor antagonistsKERN, Jeffrey C; TEREFENKO, Eugene; TRYBULSKI, Eugene et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 16, pp 4816-4818, issn 0960-894X, 3 p.Article

Novel progesterone receptor modulators with gene selective and context-dependent partial agonismBERRODIN, Thomas J; JELINSKY, Scott A; GRACIANI, Nilsa et al.Biochemical pharmacology. 2009, Vol 77, Num 2, pp 204-215, issn 0006-2952, 12 p.Article

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A study of 17p-estradiol-regulated genes in the vagina of postmenopausal women with vaginal atrophyCOTREAU, Monette M; CHENNATHUKUZHI, Vargheese M; CRABTREE, Judy S et al.Maturitas (Amsterdam). 2007, Vol 58, Num 4, pp 366-376, issn 0378-5122, 11 p.Article

Novel pyrrole-containing progesterone receptor modulatorsCOLLINS, Mark A; HUDAK, Valerie; UNWALLA, Rayomond J et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 9, pp 2185-2189, issn 0960-894X, 5 p.Article

Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin PathwayCRABTREE, Judy S; JELINSKY, Scott A; DAVE, Bhuvanesh et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 15, pp 6171-6178, issn 0008-5472, 8 p.Article

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